Victoria Belancio

Abstracts and Presentations:
Victoria P. Belancio
Biographical Narrative: Dr. Belancio was born in Berlin, Germany. She obtained her BS and MS degrees in Cytology and Genetics from Novosibirsk State University in Novosibirsk, Russia. She studied Medical Genetics at the University of Alabama at Birmingham. She received her doctoral degree in Molecular and Cellular biology from the Department of Epidemiology at Tulane University in New Orleans. She did her postdoctoral training with Dr. Prescott Deininger at Tulane University. She has been a faculty member in the Department of Structural and Cellular Biology, Tulane School of Medicine since 2008 and is a member of the Tulane Center for Aging. Dr. Belancio’s primary research interests are focused on genetic instability and cellular responses associated with the activity of mammalian retroelements. She is studying molecular mechanisms controlling the expression of and the damage from these elements in normal and cancer cells.
Selected publications:
- Wertz GW, Perepelitsa VP, Ball LA. Gene rearrangement attenuates expression and lethality of a nonsegmented negative strand RNA virus. Proc Natl Acad Sci U S A. 1998 Mar 31; 95(7):3501-6.
• Ball LA, Pringle CR, Flanagan B, Perepelitsa VP, Wertz GW. Phenotypic consequences of rearranging the P, M, and G genes of vesicular stomatitis virus. J Virology 1999 Jun; 73(6):4705-12.
• Perepelitsa-Belancio V, Deininger P. RNA truncation by premature polyadenylation attenuates human mobile element activity. Nat Genetics 2003 Dec; 35(4):363-6. [commentaries in ‘The Scientist’ and ‘Nature Reviews Genetics’]
• Astrid M. Roy-Engel, Mohamed El-Sawy, Lubna Farooq, Guy L. Odom, Victoria Perepelitsa-Belancio, Heather Bruch, Oluwatosin O. Oyeniran, and Prescott L. Deininger. Human Retroelements May Introduce Intragenic Polyadenylation Signals. Cytogenetic and Genome Research, 2005;110(1-4):365-71.
• Mohammed El-Sawy, Shubha Kale, Christine Dugan, Thuc Quyen Nguyen, Victoria Perepelitsa-Belancio, Heather Bruch, Astrid M. Roy-Engel, and Prescott L. Deininger. Nickel stimulates genetic instability through L1 retrotransposition. Journal of Molecular Biology, 2005 Nov 25;354(2):246-57.
• Belancio VP., Hedges DJ., Deininger P. LINE-1 RNA splicing and influences on mammalian gene expression. Nucleic Acid Research. 2006 Mar 22; 34(5):1512-1521
• Jinchuan Xing, Hui Wang, Victoria P. Belancio, Richard Cordaux, Prescott Deininger and Mark A. Batzer. "Emergence of new primate genes by retrotransposon-mediated sequence transduction" Proc Natl Acad Sci USA. 2006 Nov 21;103(47):17608-13.
• Belancio VP., Whelton M., Deininger P. Requirements for polyadenylation at the 3’ end of LINE-1 element. Gene. 2007 Apr 1;390(1-2):98-107
• Belancio VP., D. Hedges, and Deininger P. Mammalian non-LTR retrotransposons: For better or worse, in sickness and in health. Review. Genome Research 2008 Mar;18(3):343-58
• Belancio VP., Roy-Engel AM., Deininger P. The impact of multiple splice sites in human L1 elements. Gene. 2008 411(1-2):38-45
• Wallace NA., Belancio VP., and Deininger P. L1 mobile element expression causes multiple types of toxicity. Gene 2008 Aug 1;419(1-2):75-81
Contact info: vperepe@tulane.edu