Selected Publications
V. Perepelitsa-Belancio and P. Deininger. (2003) RNA truncation by premature polyadenylation attenuates human mobile element activity. Nature Genetics 35,363-366. commentaries in 'The Scientist' and 'Nature Reviews Genetics'.
G.L. Odom, J.L. Robichaux, and P.L. Deininger. (2004) Predicting mammalian SINE subfamily activity from A tail length. Molecular Biology and Evolution. 21,2140-8.
M. El-Sawy and P. Deininger. (2005) Tandem insertions of ALU elements. Cytogenetic and Genome Research Research 108,58-62.
A.M. Roy-Engel, M. El-Sawy, L. Farooq, G.L. Odom, V. Perepelitsa-Belancio, H. Bruch, O.O. Oyeniran, and P.L. Deininger (2005) Human retroelements may introduce intragenic polyadenylation sites. Cytogenetic and Genome Research 110,365-71.
M. El-Sawy, S.P. Kale, C. Dugan, T.Q. Nguyen, V. Belancio, H. Bruch, A.M. Roy-Engel, P.L. Deininger. (2005) Nickel stimulates L1 retrotransposition by a post-transcriptional mechnism. J. Mol. Biol. 354:246-57.
Stephen L. Gasior, Melanie Palmisano, Prescott L. Deininger. (2005) Alu-linked hairpins efficiently mediate RNA interference with less toxicity than H1-expressed shRNAs. Anal Biochem. 349,41-48.
S. Gasior, T. Wakeman, B. Xu, and P. Deininger. (2006) The Human LINE-1 Retrotransposon Creates DNA Double-Strand Breaks. J. Mol. Biol. 357,1383-93.
V.P. Belancio, D. Hedges, P. Deininger. (2006) LINE-1 RNA splicing and influences on mammalian gene expression. Nucleic Acids Res. 34,1512-21.
J. Xing, H. Wang, V.P. Belancio, R. Cordaux, P.L. Deininger and M.A. Batzer (2006) Emergence of new primate genes by retrotransposon-mediated sequence transduction. Proc. Natl. Acad. Sci. 103:17608-13.
V.P. Belancio, M. Whelton, and P. Deininger (2007) Requirements for polyadenylation at the 3’ end of LINE-1 elements. Gene 390,98-107.
S. Gasior, G. Preston, D. Hedges, N. Gilbert, J. Moran and P. Deininger (2007) Characterization of pre-insertion loci of de novo L1 inserts. Gene 390,190-198.
DJ Hedges and PL Deininger (2007) Inviting instability: Transposable elements, double-strand breaks, and the maintenance of genome integrity. Mutation Research 616,46-59.
Selected Reviews
P. Deininger and M. Batzer (2002) Mammalian Retroelements. Genome Research 12:1455-1565.
M. Batzer and P. Deininger (2002) Alu repeats and human genomic diversity. Nature Reviews: Genetics. 3:370-379.
P. Deininger, J.V. Moran, M.A. Batzer, and H.H. Kazazian, Jr. (2003) Mobile elements and mammalia genome evolution. Curr. Opin. Genet. & Dev. 13,1-8
P. Deininger (2006) Alu elements. Genomic Disorders: The Genomic Basis of Disease (Lupski and Stankiewics, eds) Humana Press, pp 25-39.
Contact info: pdeinin@tulane.edu