Tulane Cancer Center Members: R
Faculty Membership Application and Membership Definitions

---

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Ramayya, Roberts, Rose, Rowan

Meera S. Ramayya, M.D., M.S.
Assistant Professor of Pediatrics, Section of Endocrinology
TCC Contributing Member
mramayya@tulane.edu
1430 Tulane Ave., Box SL-37, New Orleans, LA 70112-2699
(504) 988-5456

Biographical Narrative:
Dr. Ramayya received her MBBS from Lady Hardinge Medical College and Hospital, University of Delhi, New Delhi, India, in 1970, and her Diploma in Child Health from The College of Physicians and Surgeons of Bombay the next year. Following her postgraduate work in Bombay, she served as senior house surgeon (pediatrics) at the Institute of Child Health in Hyderabad, India (1973), and as senior house officer (pediatrics) at the Sorrento Maternity Hospital (1974) and at the Selly Oak Hospital (1975) in Birmingham, UK. She started her pediatric residency in the United States in 1976 at Cook County Children's Hospital, Chicago, Illinois, and continued her residency the following year at the University of South Florida in Tampa. Her residency was followed by a five-year fellowship in Pediatric Endocrinology at the University of Washington in Seattle (1978 - 1983), and three years as a clinical associate at the National Institute of Child Health and Human Development at the National Institutes of Health (1993 - 1996). She also functioned as a consultant in Pediatric endocrinology on the MEDCON team of University of Washington (1980 - 1992). In 1994, she received a Masters Degree in Administrative Medicine from the University of Wisconsin. Immediately prior to joining the Tulane faculty, she practiced general pediatrics and pediatric endocrinology in the Greater Seattle area and was a consultant in pediatric endocrinology at the Swedish Medical Center in Seattle. In addition, she worked as a Research Scientist in the Department of Surgery at the Children's Hospital and Regional Medical Center, Seattle (1998 - 2000), and collaborated with investigators at the Fred Hutchinson Cancer Research Center in Seattle as a visiting scientist in the Division of Human Biology Program in Cancer Biology (2000 - 2004). Dr. Ramayya's research interests are in the biology of endocrine-related tumors. She had excellent research training at the NIH, and while at the NIH she cloned the human Steroidogenic Factor-1 (hSF-1) gene and studied its expression in human tissues. She is a recipient of travel grant awards from The Endocrine Society and the Lawson Wilkins Pediatric Endocrine Society for her work in the area of hSF-1. At Tulane, she plans to develop an independent research career in molecular signaling in breast and ovarian cancers.

Todd Roberts, M.D.

Diego Rose, M.D.
Associate Professor of Community Health Sciences
diego@tulane.edu
(504) 988-5742
1430 Tulane Ave., Box SL-29, New Orleans, LA 70112-2699

Brian Rowan, Ph.D.
Associate Professor of Structural and Cellular Biology (Anatomy)
TCC Program Member
browan@tulane.edu
(504) 988-1365
1430 Tulane Ave., Box SL-49, New Orleans, LA 70112-2699
Dr. Rowan's faculty listing and research interests on the SCB website:
http://www.som.tulane.edu/anatomy/faculty/browan.htm

Biographical Narrative:
Dr. Rowan received his Ph.D. in pharmacology and cancer therapeutics from the State University of New York at Buffalo in 1994. His thesis research involved Structural and Functional Characterization of Glucocorticoid Receptors in the P1798 Mouse Lymphosarcoma. From 1994 - 2000, he was a postdoctoral fellow in Molecular and Cellular Biology at Baylor College of Medicine in Houston, TX. In 2000, he joined the faculty of the Medical College of Ohio in Toledo as an assistant professor in the Biochemistry and Molecular Biology Department. Dr. Rowan has several awards to his credit, including the Sigma Xi Award for Excellence in Research, 1988, and the American Association for Cancer Research Young Investigator Scholar Award, 1999 and 2000. He is a reviewer for several medical journals, including Cancer Research, Endocrinology, Journal of Biological Chemistry, Molecular Cell, Molecular and Cellular Biology, Molecular Endocrinology and Steroids, and is a member of the American Association for Cancer Research and the Endocrine Society. Dr. Rowan joins the Tulane University Health Sciences Center faculty as Associate Professor in the Department of Structural and Cellular Biology. His research seeks to define the molecular mechanisms governing steroid receptor action in normal and disease states of female reproductive tissues with the aim of developing new therapies and improving existing therapies for breast cancer, gynecological malignancies, contraception and postmenopausal hormone replacement therapy.

Research Interests

Recent Publications:

• Rowan BG, Weigel NW, O'Malley BW. Phosphorylation of steroid receptor coactivator one: identification of the phosphorylation sites and phosphorylation through the mitogen activated protein kinase pathway. J Biol Chem 275: 4475. (2000)
• Rowan BG, Garrison N, Weigel NL, O'Malley BW. 8-Bromo-cyclic AMP induces phosphorylation of two sites in SRC-1 that facilitate ligand-independent activation of the chicken progesterone receptor and are critical for functional cooperation between SRC-1 and CREB binding protein. Mol Cell Biol 20(23):8720-30 (2000)
• Kelley KM, Rowan BG, Ratnam M. Positive regulation of folate receptor alpha by estrogen receptor antagonists via G-rich element: implications in tumor targeting. Cancer Res 63(11):2820-8 (2003)
• Rowan BG, Narayanan R, Weigel NL. Analysis of receptor phosphorylation. Methods Enzymol, 364:173-202. (2003)
• Kershah SM, Desouki MM, Koterba KL, Rowan BG. Expression of estrogen receptor coregulators in normal and malignant human endometrium. Gynecol Oncol 92(1):304-13 (2004)
• Desouki MM, Rowan BG. SRC kinase and mitogen-activated protein kinases in the progression from normal to malignant endometrium. Clin Cancer Res 15;10(2):546-55 (2004)
• Shah YM, Basrur V, Rowan BG. Selective estrogen receptor modulator regulated proteins in endometrial cancer cells. Mol Cell Endocrinol 219(1-2):127-39 (2004)
• Shah Y, Rowan BG. The Src Kinase Pathway Promotes Tamoxifen Agonist Action through Phosphorylation-Dependent Stabilization of Estrogen Receptor alpha Promoter Interaction and Elevated SRC-1 Activity. Mol Endocrinol 19(3):732-48. (2005)
• Basu A, Rowan BG. Genes related to estrogen action in reproduction and breast cancer. Frontiers Biosci, in press. (2005)
• Shah Y, Kaul A, Dong Y, Ip C, Rowan BG. Selenium inhibits estrogen receptor signaling in breast cancer through decreased expression of estrogen receptor alpha mRNA. Breast Cancer Res Treat, in press. (2005)
• Shah Y, Al-Dhaheri M, Dong Y, Ip C, Rowan BG. Selenium disrupts estrogen receptor alpha signaling and restores tamoxifen sensitivity in tamoxifen resistant breast and endometrial cancer cells. Accepted to Mol Cancer Therapeutics. (2005)

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

---

Return to the top of this page.
Return to the Tulane Cancer Center homepage.

Calendars Clinical Trials Faculty Links Location News
Search Site index