Tulane Cancer Center Members: W
Faculty Membership Application and Membership Definitions

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Walsh, Wang, Ware, Washington, Weaver, Webber, Weiner, Wiese, Williams , Wimley, Wright

John W. Walsh, M.D.
Professor of Neurosurgery
Chief of Pediatric Neurosurgery
TCC Associate Member
jwalshmd@tulane.edu
(504) 988-5565, (504) 988-5793 fax
1430 Tulane Ave., Box SL-47, New Orleans, LA 70112-2699

He Wang, Ph.D.
Assistant Professor of Environmental Health Sciences

TCC Program Member
hwang2@tulane.edu
(504) 988-1081, (504) 988-1726 fax
1430 Tulane Ave., Box TW-2100, New Orleans, LA 70112-2699

 

Biographical Narrative:
Dr. Wang received his Ph.D. from the University of Sydney in 1998 and conducted research as a scientific officer at the University of New South Wales from 1998-2003. From 2003-2007, he was senior lecturer at the University of Adelaide. His main research interests are the mutagenic/carcinogenic effects of airborne particles, inflammatory reactions caused by environmental factors, and possible consequences of the inflammation.


Marcus L. Ware, M.D., Ph.D.
Assistant Professor of Neurosurgery
TCC Associate Member
mware@tulane.edu
(504) 988-5561, (504) 988-1731 fax
1430 Tulane Ave., Box SL-47, New Orleans, LA 70112-2699

 

Biographical Narrative:

Dr. Marcus L. Ware attended Tougaloo College in Jackson, Mississippi, where he majored in chemistry and graduated with a B.S. in 1993. After college, he attended Harvard Medical School and was a student in the Harvard-MIT Health Sciences and Technology Program (HST) and the MD/PhD Program. Dr. Ware completed his thesis work in the laboratory of Christopher Walsh, MD, PhD, studying molecular events in the development of the brain. After graduating in 2000, he trained as a resident in the Department of Neurological Surgery at the University of California, San Francisco. As a resident, he became interested in genes required for brain tumor formation. In 2004, he obtained a National Research Service Award from the National Institutes of Health under the mentorship of Burt Feuerstein, M.D., Ph.D., and studied genetic aberrations in gliomas.

Recent Publications:


awashington Alexander Washington, M.D.
Clinical Associate Professor of Medicine

Section of Hematology/Medical Oncology
TCC Associate Member
awashin2@tulane.edu
(504) 988-2967
1430 Tulane Ave., Box SL-78, New Orleans, LA 70112-2699

 


Michael Weaver, M.D.
Associate Professor of Surgery
mweaver@tulane.edu
(504) 988-7520
1430 Tulane Ave., Box SL-22, New Orleans, LA 70112-2699


Larry S. Webber, Ph.D.
Professor of Biostatistics, Tulane School of Public Health and Tropical Medicine
TCC Contributing Member
lwebber@tulane.edu
(504) 988-5164, (504) 988-1706 fax
1430 Tulane Ave., Box SL-18, New Orleans, LA 70112-2699
Homepage on the Epidemiology website:
http://www.biostatistics.tulane.edu/bio_pages/faculty_bio/webber.html

Biographical Narrative:
Dr. Webber received his B.S. in Mathematics from Louisiana State University at Baton Rouge in 1967. After attending Graduate School at Louisiana State University Health Sciences Center, he entered Yale University in 1967 where he completed an M.Phil. degree in Biometry and a Ph.D. degree in Biometry. Dr. Webber was appointed by the National Research Council as a Statistician with the Atomic Bomb Casualty Commission (now the Radiation Effects Research Foundation) from 1972-1974. In 1974 he took a faculty position with Louisiana State University Health Sciences Center as Head of the Planning and Analysis Core for the Bogalusa Heart Study, a long-term epidemiological investigation of cardiovascular risk factors and risk behaviors. He reached the rank of Professor in the Departments of Medicine and Biometry and Genetics in 1984. Since 1991 Dr. Webber has served as Professor and Chair, Department of Biostatistics at Tulane University School of Public Health and Tropical Medicine. He has published over 270 papers as principal author or co-author. He is a reviewer for several epidemiological and public health journals and has served on various NIH review panels. The primary focus of his research is the epidemiology of cardiovascular risk factors and risk behaviors during childhood and adolescence. Since 1987 Dr. Webber has been associated with several school-based intervention models to reduce risk factors and alter risk behaviors. Dr. Webber serves as the Principal Investigator for the Louisiana site of two multi-site clinical trials, the Child and Adolescent Trial of Cardiovascular Health (CATCH) and the Trial of Activity for Adolescent Girls (TAAG). The former is a multi-component program to reduce dietary fat, increase physical activity and reduce the onset of tobacco use in elementary school children. The latter is a multi-site trial to increase opportunities for and participation in physical activity for middle school-age girls. Dr. Webber serves as Chair of the Steering Committee for the TAAG trial.

Recent Publications:


Roy S. Weiner, M.D.
Associate Dean for Clinical Research and Education
Associate Director of Clinical Research for Tulane Cancer Center
Professor of Medicine, Pediatrics, and Epidemiology
Edward G. Schlieder Educational Foundation Chair in Medical Oncology
rweiner@tulane.edu
(504) 988-6061, (504) 988-6077 fax
1430 Tulane Ave., Box SL-68, New Orleans, LA 70112-2699

Biographical Narrative:
Dr. Weiner completed his undergraduate degree at Williams College, majoring in German and Biology. He received his M.D. in 1967 from SUNY at Brooklyn with a research emphasis in immunology. He trained in internal medicine at Johns Hopkins Hospital and at the Hospitals of the University of California in San Francisco. After a fellowship in medical oncology and immunology as a Staff Associate at the NIH, he completed a second post-doctoral fellowship in cellular immunology and immunotherapy at l'Institut de Cancerologie et d'Immunogenetique in Villejuif, France. Dr. Weiner taught at Harvard Medical School as Assistant Professor of Medicine and Research Associate at the Dana Farber Cancer Institute and the Brigham and Womens Hospital prior to joining the faculty at the University of Florida as Associate Professor of Medicine, Microbiology and Immunology and Chief, Division of Medical Oncology in 1976. He was promoted to Professor in 1981 and in 1987 began serving as the American Cancer Society Professor of Clinical Oncology. Dr. Weiner's basic research contributions are focused on human hematopoeitic stem cell physiology, cell separation and stem cell cryopreservation. The methods he developed for freezing and thawing human mononuclear cells are used widely today in basic research and in clinical stem cell transplantation. His clinical research contributed to the modern multi-drug treatment of adult leukemia and, more recently, the multimodality therapy of locally advanced breast cancer. He has published more than 140 scientific papers in peer-reviewed journals, many invited papers, and has edited several books. He is on the editorial boards of several scholarly journals and has served the AACR, ASCO, and ASH in leadership positions. Dr. Weiner began working at Tulane University in 1993 as the Edward G. Schleider Educational Foundation Professor of Medical Oncology and founding Director of the Tulane Cancer Center. Responding to the critical needs of the region, (Louisiana has the 3rd highest cancer death rate in the U.S.), Dr. Weiner has concentrated his clinical energies in community programs designed to promote early detection of cancer, especially breast cancer. He instituted the region's first comprehensive breast diagnostic center and treatment clinic, and has developed a community-based clinical research network spanning the Gulf Coast and the entire State of Louisiana.

Recent Publications:


Thomas E. Wiese, Ph.D.
Assistant Professor of Environmental Health Sciences, Tulane School of Public Health and Tropical Medicine
TCC Program Member
twiese@xula.edu
(504) 988-6376, (504) 988-6428 fax
1430 Tulane Ave., Box SL-29, New Orleans, LA 70112-2699
Homepage: http://www.ehs.tulane.edu/Faculty-Profiles/Wiese-Tom.html

Dr. Wiese received his B.S. in Biology from the University of Michigan, Flint in 1984. He carried out doctoral studies in Biochemistry on the ligand specificity of the estrogen receptor with Dr. Samuel Brooks at Wayne State University School of Medicine and obtained his Ph.D. in 1995. He was a postdoctoral fellow with Drs. William Kelce and Earl Gray at the University of North Carolina at Chapel Hill and the US EPA NHEERL, working on molecular mechanisms of endocrine disruption. In 1998 Dr. Wiese took a joint faculty position in the Environmental Health Sciences, Tulane School of Public Health and Tropical Medicine and the College of Pharmacy, Xavier University of Louisiana. This position involves active collaboration with the Environmental Endocrinology Laboratory at the Center for Bioenvironmental Research at Tulane and Xavier Universities. Dr. Wiese has published papers on the subjects of endocrine disruption, structure-activity relationships of hormone active chemicals and estrogen mediated effects on gene induction and proliferation in breast cancer cells. The primary theme of Dr. Wiese's research is molecular mechanisms involved in nuclear receptor mediated endocrine disruption. Projects underway include characterizations of gene and tissue specific effects, receptor specific effects and species specific effects of hormone active environmental chemicals. Cellular, biochemical, molecular biological and molecular modeling approaches are applied in the Wiese lab to studies of the estrogen, androgen and progestin activity of environmental contaminants.

Recent Publications:

Chris Williams
Christopher Williams, Ph.D.
Research Assistant Professor of Structural and Cellular Biology
TCC Program Member
cwillia0@tulane.edu
504-988-1562, 504-988-1687(fax)
1430 Tulane Ave., SL49, New Orleans, LA 70112


Biographical Narrative:

After receiving a Bachelor of Science in Biology from Southern University at New Orleans, Dr. Williams pursued a doctoral degree in Pharmacology at Tulane University under the tutelage of Dr. Krishna Agrawal. His research interests focused on the effects of the HIV-Tat protein in hematopoietic dysfunction in HIV-AIDS. After matriculation in 2003, Dr. Williams joined the laboratory of Dr. Frank Jones at Tulane University. Here, his research foculsed on the novel role of the ERB4 tyrosine receptor kinase as a molecular chaperone and transcriptional co-activator for Stat5a and estrogen receptor in breast cancer. Due to Hurricane Katrina, Dr. Williams continued his postdoctoral training in the laboratory of Dr. Brian Rowan at Tulane University, where his work centered on the identification and characterization of novel estrogen receptro phosphorylation sites and their impact on anti-estrogen therapy in breast cancer. Dr. Williams joined the Department of Structural and Cellular Biology as a Research Assistant Professor in 2008. Currently, Dr. Williams' work focuses on the characterization of novel ERα phosphorylation in breast cancer, as well as the impact of the NR4A orphan nuclear receptors on chemotherapeutic efficacy in various models of breast cancer.

Recent Publications:


William C. Wimley, Ph.D.
Assistant Professor of Biochemistry
TCC Program Member
wwimley@tulane.edu
(504) 988-7076, (504) 988-2739 fax
1430 Tulane Ave., Box SL-43, New Orleans, LA 70112
Homepage on the Biochemistry website:
http://www.tulane.edu/~biochem/faculty/wimley.htm

Biographical Narrative:
Dr. Wimley received his B.S. in Biophysics from the University of Connecticut, Storrs in 1985 and his Ph.D. in Biochemistry from the University of Virginia, Charlottesville in 1990. His postdoctoral studies were carried out in the Department of Physiology and Biophysics at the University of California at Irvine where he studied the structure, folding and design of proteins in membranes with Dr. Stephen H. White. During his postdoctoral tenure, Dr. Wimley received a three-year NRSA grant from the National Institutes of Health. Dr. Wimley joined the Tulane faculty in 1998 as an Assistant Professor in the Department of Biochemistry at the Health Sciences Center. The primary theme of Dr. Wimley's research is the structure, folding and design of proteins in membranes. Much of his research utilizes peptide models of membrane proteins. His laboratory uses both traditional and combinatorial chemistry to design and engineer peptide models that assemble into membrane proteins or that interact with membrane proteins. One of the laboratory's current projects is the design of membrane-spanning peptide pores using combinatorial chemistry and high-throughput screening. Such molecules will be used in antibiotic drug design, in drug delivery and in biosensor engineering. Another project in the laboratory involves the use of combinatorial chemistry and high throughput screening to design peptides that specifically interact with receptors that are overexpressed in cancer, including G-protein coupled receptors and receptor tyrosine kinases. These molecules will be used to modulate receptor activities and to target the delivery of drugs and cytotoxic agents to specific cells. Finally, the laboratory is involved in genomic and proteomic analysis of genome databases. The goal of this work is to improve the recognition and identification of membrane proteins in genomes and to improve the prediction of their structure and function.

Recent Publications:

mjwright Mary Jo Wright, M.D.
Associate Professor of Surgery
TCC Associate Member
mjwright@tulane.edu
(504) 988-2317
1430 Tulane Ave., Box SL-22, New Orleans, LA 70112



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