Molecular Genetics & Viral Oncogenesis Research Program
Cancer cannot occur without multiple genetic changes. Among these changes are the addition of viral gene expression to the cell, as well as mutations to cellular genes, either sporadic or induced by environmental mutagens. These changes ultimately lead to an overall genetic instability that contributes to the formation and progression of the tumor. This program includes investigators who study aspects of the human genome itself which naturally contribute to genetic instability, investigators who work on the genes which play a primary role in maintaining or altering genomic stability, as well as those who study the mutagenesis process and the environmental contribution to mutagenesis. These studies are relevant to translational research both in the diagnostic arena and in identification of targets for therapeutic intervention.
Program Leader
Prescott Deininger, Ph.D.
Interim Director, Tulane Cancer Center
Marguerite Main Zimmerman Chair in Basic Cancer Research
Professor of Epidemiology
Adjunct Professor of Biochemistry, Pathology, and Human Genetics
Interim Co-Director, Louisiana Cancer Research Consortium
pdeinin@tulane.edu
(504) 988-6385, (504) 988-5516 fax
1430 Tulane Ave., Box SL-66, New Orleans, LA 70112-2699
Representative project: Human Dimorphisms Caused by Sine Master Genes