PPT Slide

Multiple myeloma - malignancy of plasma cells, derived from

B-type lymphocytes, involves bone marrow, produce

multisystem disease. Laboratory finding: anemia, ESR ,

Ca , proteinuria, hyperglobulinemia, hypo __G. Albumin

Bence Jones proteins

Abnormal proteins - monoclonal spike.

75% IgG, 25% IgA less than 2% Ig D or E.

In general 66% k, 33% _

IgD 90% _

Other plasma cell dyscrasias

amyloidosis

solitary plasmacytoma

heavy chain disease

Waldenstromís macro G

idiopatic monoclonal G

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