Thyroid Function Tests

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Table of Contents

Thyroid Function Tests

Synthesis of Thyroid Hormones

Synthesis of Thyroid Hormones

Laboratory Thyroid Profile

T4 (Total)

Relationship of Thyroid-binding globulin (TBG) to total serum T4 concentration

Causes for Increased Thyroxine-Binding Globulin

Causes for Decreased Thyroxine-Binding Globulin

RTU,TBR

FT4 - I

Causes for Decreased Thyroxine or Free Thyroxine Values

Causes for Increased Thyroxine or Free Thyroxine Values (cont.)

Causes for Increased Thyroxine or Free Thyroxine Values (cont.)

TSH

Conditions That Increase Serum Thyroid-Stimulating Hormone Values

Conditions That Increase Serum Thyroid-Stimulating Hormone Values (cont.)

Conditions That Decrease Serum Thyroid-Stimulating Hormone Values*

Conditions That Decrease Serum Thyroid-Stimulating Hormone Values* (cont)

131I Uptake

Etiologies of Decreased Radioactive Iodine Uptake Values

Some Nonthyroid Illnesses that Can Affect Thyroid Tests

Thyroiditis - inflammation of the thyroid gland

Acute Bacterial Thyroiditis

De Quervainís Thyroiditis - Subacute Granulomatous Thyroiditis

PPT Slide

Subacute Painless Thyroiditis (Silent)

Riedelís Thyroiditis

PPT Slide

Hashimotoís Thyroiditis

PPT Slide

Graveís Disease

PPT Slide

PPT Slide

PPT Slide

PPT Slide

Hypothyroidism

Goiter

Non-toxic Goiter

Non-toxic Goiter

Non-toxic Goiter

Table I: Summary of Thyroid Profile and 131I Uptake Results in Disorders Associated with Thyrotoxicosis, Hypothyroidism and Alterations in Thyroid-binding Globulin*

Author: Pathology Dept.

Email: ross.klingsberg@tulane.edu

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