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The field of Genomics has emerged from the information gained from the sequencing of eukaryotic and prokaryotic genomes. In this course we will examine the human genome -- all 3,200,000,000 base pairs! Not nucleotide by nucleotide, but rather with a focus on the structure of the chromosome and the function of protein coding genes -- how these are synthesized, regulated, repaired and replicated. Incorporated into our discussions are the tools of molecular biology as they apply to diagnostics of genetic and infectious diseases, therapeutics and rationale drug design as well as the ultimate tool of molecular medicine -- gene therapy. Biochemical Genomics is presented in a lectured based format that correlates clinical issues with the fundamental priniciples of molecular biology. There will be assigned readings in the text Human Molecular Genetics 2 and students are expected to incorporate reading into their course study. There are two, hour long exams, each covering 50% of the material. Grades will be determined by the average of these two exams, which will be equally waited. For more information, please see:
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